Bennett Landman, M.Eng.
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Note: This page is no longer maintained. I graduated in August 2008 and joined the Johns Hopkins Biomedical Engineering Department. Curretly (Summer 2009), I am in the process of moving to Vanderbilt University. Please look for my new website once the transition is complete.
CURRICULUM VITAE
Bennett A. Landman
CONTACT INFORMATION
Office Address
720 Rutland Ave., Traylor 606
The Johns Hopkins University
Baltimore, MD 21205
Tel: (410) 917-6166 E-mail: landman@jhu.edu
Fax: (443) 451-5506 Homepage: http://iacl.ece.jhu.edu/~bennett
RESEARCH INTERESTS
Magnetic
resonance imaging and statistical analysis with emphasis on medical imaging;
particularly, 1) quantitative investigation of diffusion inferred tissue
microstructure through tensor and non-tensor biophysical models, 2) robust and
optimal methods for medical image analysis and model estimation, 3) development
of technologies to transition research concepts into tools for clinical
investigation.
EDUCATION
Ph.D. 2008 Biomedical Engineering
(Exp. 8/08) Johns Hopkins University School of Medicine,
Baltimore, MD
Thesis: Diffusion Imaging of the In Vivo Cerebellum and Spinal Cord
Advised by Jerry Prince and Susumu Mori. Image Analysis and
Communications Laboratory.
M.Eng. 2002 Electrical Engineering and Computer Science
Massachusetts
Institute of Technology, Cambridge, MA
Thesis: Broadband Nanosensing using Heterodyne
Interferometry.
Advised by Dennis Freeman.
Research Laboratory for Electronics.
B.S. 2001 Electrical Engineering and Computer Science
Massachusetts
Institute of Technology, Cambridge, MA
Minors in Mechanical
Engineering and Economics.
PROFESSIONAL EXPERIENCE
|
Aug. 2004 – Aug. 2008 |
Ph.D. Candidate in
Biomedical Engineering Johns Hopkins University
School of Medicine, Department of Biomedical Engineering · Researching central nervous system morphology through
structural and diffusion weighted magnetic resonance imaging (MRI),
considering challenges from pulse sequence design to development of image
analysis algorithms. · Investigating multi-compartment, sub-voxel methods
including spherical harmonics and adaptive sampling schemes. |
|
Jan. 2003 – Jun. 2004 |
Senior Software Engineer Neurobehavioral Research,
Inc., Corte Madera, CA · Researched cortical atrophy associated with aging,
alcoholism, and drug use. · Spearheaded efforts to validate and integrate emerging
MRI analysis methods. · Developed custom analysis techniques and integrated
software based on voxel-based morphometry (VBM), statistical parametric
mapping (SPM), and FMRIB Software Library (FSL) tools. · Actively involved in writing peer-reviewed publications,
research presentations, grant preparation, academic conferences, and hiring
new employees. |
|
Sep. 2001 – Dec. 2003 |
R&D Architect ViaSense, Inc., Emeryville, CA · Developed video compression technology based on
bio-signal processing research using perceptual modeling, adaptive
processing, and advanced compression techniques. · Co-invented generalized processing methods to
integrate perceptual information into modern visual coding algorithms,
including MPEG2, MPEG4, H.263, JPEG. · Achieved a two-fold improvement in compression over
industry leaders. · Gained image and video processing expertise in
enhancement, detection, and coding. |
|
Jan.2001 – Feb. 2002 |
Research Assistant MIT Research Laboratory for
Electronics · Designed and built hardware/software system for
detecting broadband sub-micron motion, for study of transient motion in
micro-mechanical (MEMS) and biological systems. · Completed research leading to a master’s thesis
project. |
|
Jun. 1999 – Sep. 2001 |
Software Engineer ViaSense, Inc., Emeryville, CA · Created demonstration applications for quality
comparisons and algorithms exhibition. · Implemented core algorithms for perceptual
processing in an image processing toolbox. · Deployed a proxy server for real time content
optimization for handheld devices. |
|
Jun. 1998 – Jun. 1999 |
Programmer Analyst U.C. Berkeley Department of
Molecular and Cell Biology · Developed an improved visual stimulus generator for
retinal response experiments. · Created analysis software for electrode array time
series data to determine cell types and response properties. |
|
Jan. 1998 – Jun. 1998 |
UROP Programmer MIT List Media Art Center · Developed a web site and database interface for a
digital journal that allowed sponsors to barcode scan project demos during
open houses, and then retrieve personalized web-based biographical
information and project status. · Designed a secure web site for the Digital Life
Consortium’s sponsors and research team. |
· Student Travel Award, International Society for Magnetic Resonance in Medicine (2008)
· ISMRM White Matter Study Group Poster Award Finalist (2007)
· Student Travel Award, Organization for Human Brain Mapping (2007)
· Student Travel Award, International Society for Magnetic Resonance in Medicine (2007)
· Best Poster, Johns Hopkins Biomedical Engineering PhD Retreat (2006)
· Student Travel Fellowship, Organization for Human Brain Mapping (2006)
· Student Travel Award, International Society for Magnetic Resonance in Medicine (2006)
· National Defense Science and Engineering Graduate Fellowship (DOD/ONR) (2006-2009)
· National Science Foundation Graduate Research Fellowship Honorable Mention (2005)
· National Science Foundation Graduate Research Fellowship Honorable Mention (2004)
· Tau Beta Pi Engineering Honor Society Member (2001)
· Eta Kappa Nu Engineering Honor Society Member (2000)
Professional Memberships
Scientific Review
1. G. Fein, V. Di Sclafani, C. Taylor, K. Moon, J. Barakos, H. Tran, B. Landman, and R. Shumway. “Controlling for premorbid brain size in imaging studies: T1-derived cranium scaling factor vs. T2-derived intracranial vault volume”. Psychiatry Research: Neuroimaging. 131(2):169-76. July 2004.
2. G. Fein, and B. Landman. “Treated and treatment-naive alcoholics come from different populations”. Alcohol. 35(1):19-26. June 2005.
3. C. Harper, I. Matsumoto, A. Pfefferbaum, E. Adalsteinsson, E. Sullivan, J. Lewohl, P. Dodd, M. Taylor, G. Fein, and B. Landman. “The Pathophysiology of 'Brain Shrinkage' in Alcoholics - Structural and Molecular Changes and Clinical Implications”, Alcoholism: Clinical & Experimental Research. 29(6):1106-1115. June 2005.
4. G. Fein, B. Landman, H. Tran, J. Barakos, K. Moon, V. Di Sclafani, and R. Shumway. “Statistical Parametric Mapping of Brain Morphology: Sensitivity is Dramatically Increased by Using Brain-Extracted Images as Inputs”. NeuroImage. 30(4):1187-95. May 2006.
5. G. Fein, B. Landman, H. Tran, S. McGillivray, P. Finn, J. Barakos, and K. Moon. “Brain Atrophy in Long-Term Abstinent Alcoholics Who Demonstrate Impairment on a Simulated Gambling Task Corresponding”. NeuroImage. 32(3):1465-71. September 2006.
6. B. A. Landman, J. A. Farrell, C. K. Jones, S. A. Smith, J. L. Prince, P. C. van Zijl, and S. Mori. “Effects of Diffusion Weighting Schemes on the Reproducibility of DTI-derived Fractional Anisotropy, Mean Diffusivity, and Principal Eigenvector Measurements at 1.5T”, NeuroImage. 36(4): 1123-1138. July 2007.
7. J. A. Farrell, B. A. Landman, C. K. Jones, S. A. Smith, J. L. Prince, P. C. van Zijl, and S. Mori. “Effects of SNR on the Accuracy and Reproducibility of DTI-derived Fractional Anisotropy, Mean Diffusivity, and Principal Eigenvector Measurements at 1.5T”, Journal of Magnetic Resonance Imaging. 26(3): 756-767. August 2007.
8. A. Ozturk, A.D. Sasson, J.A.D. Farrell, B. A. Landman, A. C. B. S. da Motta, A. Aralasmak, and D. M. Yousem. “Regional Differences in Diffusion Tensor Imaging Measurements: Assessment of Intra-Rater and Inter-Rater Variability”, American Journal of Neuroradiology. In press 2008.
9. B. Landman, J. Farrell, H. Huang, J. Prince, and S. Mori. “Diffusion Tensor Imaging at Low SNR: Non-monotonic behaviors of tensor contrasts”, Magnetic Resonance Imaging. In press 2008.
10. H.Shinagawa, E.Z. Murano, J. Zhuo, B. Landman, R.P. Gullapalli, J.L. Prince, and M. Stone. “Human tongue muscle fiber tracking during rest and tongue protrusion with oral appliance: A preliminary study with diffusion tensor imaging”, Acoustical Science and Technology. In press 2008.
Submitted for Publication
11. M. Stone, E. Murano, H. Shinagawa, A. Salama, J. Prince, X. Liu, R. Ord, R. Gullapalli, J. Zhuo, B. Landman, and H. Agarwal. “Tongue Motion Patterns in Two Glossectomy Patients During Speech: A Pilot Study”, International Journal of Oral and Maxillofacial Surgery. Submitted September 2007
12. B. A. Landman, P-L Bazin, J. L. Prince, “Robust Estimation of Spatially Variable Noise Fields: Applications to Diffusion Tensor Imaging”, NeuroImage, Submitted February 2008
1.
B. A. Landman, P-L. Bazin, and J. L.
Prince. “Diffusion
Tensor Estimation by Maximizing Rician Likelihood”, In Proceedings of the 2007 International Conference
on Computer Vision Workshop on Mathematical Methods in Biomedical Image
Analysis, Rio de Janeiro, Brazil, October 2007. (Oral
Presentation)
2.
B. A.
Landman, J. A.D. Farrell, S. A. Smith, P. A. Calabresi, P. C.M. van Zijl,
J. L. Prince. “Robust Maximum Likelihood Estimation in Q-space MRI”, In Proceedings of the 2008 IEEE International
Symposium on Biomedical Imaging, Paris, France, May 2008 [Poster]
3.
J. A. Bogovic, A. Carass, J. Wan, B. A. Landman, and J. L. Prince.
“Automatically identifying white matter tracts using cortical labels,” In Proceedings of the 2008 IEEE International
Symposium on Biomedical Imaging, Paris, France, May 2008
Submitted for Publication
4.
B. A. Landman,
P-L. Bazin, and J. L. Prince. “Tensor Interpolation by Concise Linear
Estimation of Anisotropy and Rotation”, In Proceedingsof
the 11th International Conference on Medical Image Computing and Computer
Assisted Intervention, New York, NY, Submitted March 2008.
1.
Fein, G.
and B. Landman. “Cognitive
Function and ‘Brain Shrikage’ in Long-Term Abstinent Alcoholics”. Alcoholism: Clinical & Experimental
Research. International Society for
Biomedical Research on Alcoholism 12th World Congress on Biomedical Alcohol
Research, Heidelburg/Mannheim, Germany. 28(8) Supplement:79A. October 2004
2.
J.A.D
Farrell, B.A. Landman, C.K. Jones, S.A. Smith, J.L. Prince, P.C.M. van
Zijl, and S. Mori. “Effects of Scan Repetition on DTI-derived Fractional
Anisotropy Measures at 1.5T”, Workshop on
Imaging Myelin, Formation, Destruction and Repair. Vancouver, Canada, 8-10
February 2006
3.
H.
Huang, J. L. Prince, A. Carass, B. Landman, P. C. van Zijl, and S. Mori.
“Corico-cortical connectivity revealed by DTI-based tractography”, International Society for Magnetic Resonance
in Medicine, Seattle, Washington, May 2006
4.
J. A.
Farrell, B. A. Landman, C. K. Jones, S. A. Smith, J. L. Prince, P. C.
van Zijl, and S. Mori. “Effects of Diffusion Weighting Scheme and SNR on
DTI-derived Fractional Anisotropy at 1.5T”, International
Society for Magnetic Resonance in
Medicine, Seattle, Washington, May 2006
5.
B. A.
Landman, J. A. D. Farrell, S. Mori, P. C.M.
van Zijl, and J. L. Prince. “Optimal
Partitioning of Diffusion Weighting Schemes”, International Society for Magnetic Resonance in Medicine, Seattle
Washington, May 2006 [Poster]
6.
B. A.
Landman, J. A. Farrell, S. Mori, P. C. van
Zijl, and J. L. Prince. “On
the Coregistration of Diffusion Weighted Images”, International Society for Magnetic Resonance in Medicine, Seattle
Washington, May 2006 [Poster]
7.
S. I. Choi, A. H. Sinofsky, B. A. Landman,
S. L Perlman, R. W Baloh, D. S Zee, A. W. Toga, J. L. Prince, and S.H. Ying,
“Volumetric Analysis of Cerebellar Subregions and Functional Correlations in
Spinocerebellar Ataxia Type 2 (SCA2): Evidence for a Developmental as well as
an Acquired Component to Parenchymal Atrophy”, Organization for Human Brain Mapping, Florence, Italy, June 2006
8.
A. H.
Sinofsky, B. A. Landman, S. Chowdhury, A. Gambini, S. Mori, D. S. Zee,
J. L. Prince, and S. H. Ying. “Diffusion-weighted MR imaging of the cerebellar
peduncles as a surrogate measure of cerebellar degeneration”, Organization for Human Brain Mapping,
Florence, Italy, June 2006
9.
M. B. Wheeler, B. A. Landman,
S. I. Choi, A. H. Sinofsky, D. S. Zee, S. H. Ying, and J. L. Prince. “MR CAVE:
Multi-atlas Robust Cerebellar Automated Volume Estimation”, Organization for Human Brain Mapping,
Florence, Italy, June 2006
10.
B. A.
Landman, S. Chowdhury, A. H.
Sinofsky, S. Mori, D. S. Zee, J. L. Prince, and S. H. Ying. “s-Image Representation of Diffusion Tensor Contrast and
Fiber Geometry: Leukometric Analysis in the Brainstem and Cerebellum”,
Organization for Human Brain Mapping,
Florence, Italy, June 2006 [Poster]
11.
B. A.
Landman, S. Chowdhury, A. H.
Sinofsky, A. S. K. Liu, S. Mori, D. S. Zee, J. L. Prince, and S. H. Ying. “Delineation
of Cerebellar Fiber Tracts on Anatomically Aligned Planes with ViPAR, a Novel
MRI Visualization and Manipulation Tool”, Organization for Human Brain Mapping, Florence, Italy, June 2006 [Poster]
12.
S. H. Ying,
J. A. Freedlander, D. C. Roberts, B. A. Landman, and D. S. Zee. “The
cerebellar substrate of vergence adaptation: an fMRI study”, Society for Neuroscience, Atlanta,
Georgia, October 2006
13.
H. Shinagawa, E. Z. Murano, J. Zhuo,
R. P. Gullapalli, B. Landman, J. L.
Prince, and M. Stone. “Tongue muscle fiber tracking during tongue protrusion
and rest”. Acoustical Society of America,
Honolulu, Hawaii, December 2006
14.
H. Shinagawa, E. Z. Murano, J. Zhuo, R. P. Gullapalli, B. Landman, J. L. Prince, and M. Stone.
“Human Tongue Myoarchitecture with Oral Appliance, Using Diffusion Tensor
Imaging.” International American and
Canadian Associations for Dental Research. New Orleans, Louisiana, #1885.
March 2007
15.
M. C. Ng,
S. A. Smith, J. S. Gillen, B. A. Landman, D. K. Luk, Y. Hu, P. C. van Zijl,
and E. S. Yang. “Improved distortion correction in cerebral and spinal DTI using
interleaved reversed gradients”, International
Society for Magnetic Resonance in Medicine, Berlin, Germany, May 2007
16.
B. A.
Landman, J. A. Farrell, S. Mori, P. C. van
Zijl, and J. L. Prince. “Tradeoffs
Between Tensor Orientation and Anisotropy in DTI: Impact of Diffusion Weighting
Scheme”, International Society
for Magnetic Resonance in Medicine, Berlin, Germany, May 2007 [Poster]
17.
B. A.
Landman, H. Huang, J. L.
Prince, and S. H. Ying. “A
Window for High-Resolution Post-Mortem DTI: Mapping Contrast Changes in Neural
Degeneration,” International
Society for Magnetic Resonance in Medicine, Berlin, Germany, May 2007 [Poster]
18.
B. A.
Landman, S. Mori, and J. L.
Prince. “Systematic
Evaluation of Linear and Nonlinear DTI Estimation Methods: An Open Framework,” International Society for Magnetic
Resonance in Medicine, Berlin, Germany, May 2007 [Poster]
19.
A. X.
Du, B. A. Landman, D. S. Zee, J. L. Prince, and S. H. Ying. “Diffusion
Tensor Imaging Reveals Disease-Specific Dentate Nucleus Changes in Cerebellar
Degeneration,” Organization
for Human Brain Mapping, Chicago, Illinois, June 2007
20.
B. A.
Landman, A. X. Du, W. D.
Mayes, J. L. Prince, and S. H. Ying, “Diffusion
Tensor Imaging Enables Robust Mapping of the Deep Cerebellar Nuclei,”
Organization for Human Brain Mapping,
Chicago, Illinois, June 2007 [Poster]
21.
B. A.
Landman, J. A. D. Farrell,
N-L. Patel, S. Mori, and J. L. Prince, “DTI
Fiber Tracking: The Importance of Adjusting DTI Gradient Tables for Motion
Correction. CATNAP – A Tool to Simplify and Accelerate DTI Analysis,”
Organization for Human Brain Mapping,
Chicago, Illinois, June 2007 [Poster]
22.
A. X. Du, J. L. Cuzzocreo, B. A. Landman, S. I. Choi, R. W. Baloh, S. L. Perlman, J. L. Prince,
T. O. Crawford, A. W. Toga, D. S. Zee, and S. H. Ying. “Posterior fossa volumes
as an indicator of early-onset cerebellar degeneration,” Society for Neuroscience, San Diego, California, November 2007
23.
B. A. Landman, P-L. Bazin, and J. L. Prince, “Robust DTI Noise Level
Estimation Improves RESTORE Tensor Estimation,” International Society for Magnetic
Resonance in Medicine, Toronto,
Canada, May 2008 [Poster]
24.
B. A. Landman, P-L. Bazin, and J. L. Prince, “Robust Diffusion Tensor Estimation
by Maximizing Rician Likelihood,” International Society for Magnetic Resonance in
Medicine, Toronto, Canada, May 2008 [Poster]
25.
B. A. Landman, J. A.D. Farrell, S. A. Smith, P. C.M. van
Zijl, and J. L Prince, “Q-Space
Diffusion Weighted MRI Analyzed with Maximizing Rician Likelihood Improves
Reliability and Tissue Contrast,” International
Society for Magnetic Resonance in Medicine, Toronto, Canada, May 2008 (Oral
Presentation)
26.
B. A. Landman, J. A.D. Farrell, S. A. Smith, P. A.
Calabresi, P. C.M. van Zijl, and J. L Prince, “Exploring the Information
Content of q-Space Diffusion Weighted Imaging: Application to Multiple
Sclerosis (MS) Spinal Cord Lesions,”
International
Society for Magnetic Resonance in Medicine, Toronto, Canada, May 2008 [Poster]
27.
D. J.
Peterson, B. A. Landman, and L. E.
Cutting. “The impact of robust tensor estimation on voxel-wise analysis of DTI
data,” International Society for Magnetic
Resonance in Medicine, Toronto, Canada, May 2008
28.
S. A.
Smith, V. Belegu, B. A. Landman, B.
A. Chodkowski, J. A. Farrell, P. C. van Zijl, and J. W. McDonald. “Quantitative
Assessment of Traumatic Spinal Cord Injury with Diffusion Tensor and
Magnetization Transfer MRI,” International
Society for Magnetic Resonance in Medicine, Toronto, Canada, May 2008
29.
B. Lucas, B. Landman, J. Prince, and D. Pham, “MAPS: A
Free Medical Image Processing Pipeline,” Organization for Human Brain Mapping, Melbourne,
Australia, June 2008. Submitted January 2008.
Submitted
for Publication
30.
D.
Bonekamp, B. Landman, P. A.
Calabresi, and D. Reich, “In Multiple Sclerosis, Tract Based Spatial Statistics
reveal that Corpus Callosum Diffusion Tensor Imaging Abnormalities are
associated with Cognitive Dysfunction,” Radiological
Society of North America, Chicago, Illinois, November 2008
31.
B. A. Landman, J. A.D. Farrell, S. A. Smith, P. A.
Calabresi, P. C.M. van Zijl, and J. L Prince, “Optimal Likelihood
Analysis of Q-Space MRI,” National
Institute of Biomedical Imaging and Bioengineering (NIBIB) 2008 Training
Grantees Meeting,
Bethesda, Maryland, June 2008
1. B. Landman. “Broadband Nanosensing using Heterodyne Interferometry”. Massachusetts Institute of Technology Master of Engineering Thesis. February 2002.
1. Optimized acquisition schemes for DTI: reproducibility and reliability. Radiology MR Division Retreat, Johns Hopkins School of Medicine. October 13, 2006. Invited by Dr. Peter van Zijl.
2. A statistical approach to data modeling in diffusion tensor imaging. Biostatistics Seminar, Johns Hopkins School of Public Health. August 14, 2007. Invited by Dr. Brian Caffo.
3. Diffusion Tensor Estimation by Maximizing Rician Likelihood, Workshop on Mathematical Methods in Biomedical Image Analysis. October 14, 2007
4. Introduction to Diffusion Tensor Imaging (Guest Lecture), Medical Image Analysis, Johns Hopkins University. November 29, 2007. Invited by Dr. Dzung Pham.
5.
Statistical
Analysis of Diffusion Weighted MRI, Neuroradiology Seminar, Johns Hopkins
University. April 8, 2008. Invited by Dr. Alena Horska
6. Magnetic Resonance Imaging of the Brain (Guest Lecture), Advanced Topics in Magnetic Resonance Imaging, Johns Hopkins University. April 17, 2008. Invited by Dr. Nael Osman.
7. Q-Space Diffusion Weighted MRI Analyzed with Maximizing Rician Likelihood Improves Reliability and Tissue Contrast, International Society for Magnetic Resonance in Medicine, May 5, 2008
Graduate Support
Pending Support
1.
Computer Science
Logo Style, University of California at Berkeley Extension. High School
Level, Academic Talent Development Program. TA. 20 students. Summer 1994.
2. Programming in Scheme, University of California at Berkeley Extension. High School Level, Academic Talent Development Program. TA. 20 students. Summer 1996.
3.
Statistical
Methods in Imaging, Johns Hopkins University. Advanced
Undergraduate/Graduate Level in Biomedical Engineering, TA under Prof. Bruno
Jednyak. 15 students. Spring 2007.
4. Signals and Controls, Johns Hopkins University. Undergraduate Level in Biomedical Engineering. TA under Prof. Michael Miller. 57 students. Spring 2007.
5. Technology Fellow: Signals and Controls, Johns Hopkins University. Applied for and awarded an educational grant: “Development of Online Resources for the BME Signals Course” ($4000 total costs). Supervised graduate student Issel Lim and senior undergraduates Pavan Dalal and William Feng under Prof. Michael Miller. Guest lectured to 120 students. Winter-Spring 2008.
Last Updated: Wednesday July 22, 2009
© Copyright 2007, Bennett Landman. All rights reserved.